Maternal age and BMI as risk factors for rectovaginal colonization with group B streptococcus

Four key methods for figuring out parturients who want prophylaxis Streptococcus Group B (ESB) are presently used: a) Risk-based methods (background). b) primarily based on prepartum tradition, c) PCR for intrapartum microorganisms and d) PCR for these at risk of neonatal illness Streptococcus.

Also learn: ECCMID 2022: Treatment of bacteremia in immunocompromised sufferers

Canada, the United Kingdom and different European nations use risk factors for the therapy of ESB (earlier ESB an infection, bacteriuria brought on by ESB throughout present being pregnant, maternal intrapartum fever > 38 °C and rupture of membranes > 18 hours). A sound technique, 70% of girls with these damaging factors and greater than 50% of puerperal ladies with ESB puerperal an infection have none of those factors.

Against this background, a Danish work was printed International Journal of Gynecology and Obstetrics On September 10, 2022, risk factors had been launched to incorporate maternal age and pre-pregnancy maternal BMI to assist within the specification of ESB illness risk.


902 Danish pregnant ladies handled on the hospital degree had been included. Premature births (as much as 37 weeks), kids beneath 18 years of age, ladies who acquired antibiotics after 35 weeks, and ladies with difficulties speaking with the group had been excluded.

Groups had been divided in accordance with their age (<25, 25 to 34, 35 to 40 and ≥ 40 years) and their pre-pregnancy BMI: underweight (<18.5 kg/mTwo), regular weight (18.5 to 24.9 kg/mTwo), chubby (25.0 to 29.9 kg/mTwo) and weight problems (≥ 30.0 kg/mTwo). Confounding factors such as parity, gestational age, vaginal supply and smoking had been included. A optimistic rectal ESB tradition obtained throughout supply from all contributors was the research consequence.

Learn extra: Risk of early neonatal sepsis in low-risk infants


Results confirmed that inclusion of girls older than 40 years as a risk issue elevated sensitivity from 21 to 26%, lowering specificity from 90 to 87%, whereas BMI ≥ 25 elevated sensitivity from 21 to 57%, lowering specificity from 90 to 59. . % as prenatal technique for ESB.

Practical message

In addition to factors already identified, maternal age above 40 years and BMI above 25 kg/m had been included.Two confirmed vital ancillary significance.

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